Drug Pricing and Affordability

Keep up with our comprehensive coverage of administrative and legislative activity and what it means for industry, plans, providers, and patients.

IRA Negotiation Creates Ripple Effects Across Drug Markets

Medicare negotiation has ripple effects across therapeutic markets, requiring manufacturers to reassess strategies to stay ahead of the changing drug landscape.

IRA Drug Price Negotiation Impact on Cardiovascular Drugs

A new Avalere white paper raises important considerations on potential added lifecycle pressures for sponsors of cardiovascular disease products.

Ashley Flint

How Will 340B Discounts Interact with Negotiated Drugs’ MFP?

The IRA requires covered entities to pay the lesser of a drug’s 340B ceiling price and MFP, presenting operational complications for manufacturers and providers.

Mark Gooding

Court Ruling Will Limit Accumulators

A district court’s decision to strike down the 2021 NBPP is the latest policy update on the use of copay adjustment programs, but questions persist.

How Can Manufacturers Help Shape Medicare Negotiations?

Manufacturers should reevaluate CMS engagement strategies as soon as possible to maximize the opportunity to influence the IPAY 2026 Medicare negotiations.

Miron Dilmanian

Manufacturers Should Assess Wastage to Inform Mitigation Strategy

Manufacturers impacted by the Part B discarded drug refund policy should assess claims billing and adjudication patterns to inform mitigation strategy.

Will Part D Redesign Lower OOP Costs for HIV Care?

The IRA’s Part D redesign could lower out-of-pocket costs for people with HIV; providers can help make sure their patients are aware of these changes.

What is the Role of 340B Grantees?

Some federal grant recipients use 340B program eligibility to expand their reach and services provided to a wide range of patient populations.

Laura Housman

Video: Unpacking the Implications of the Negotiated Drug List, Part 1

Delve into the far-reaching implications of the recently announced negotiated drug list as Avalere experts provide insights and answers to pressing questions surrounding CMS's landmark decision on Part D drug pricing and its impact on manufacturers, patients, and the future healthcare landscape.

Lance Grady

CMS Selects First 10 Drugs for Medicare Negotiation

CMS selected 10 Part D drugs for the first year of negotiation. Stakeholders should consider engagement opportunities and evaluate broader therapeutic dynamics.

How Will the IRA Impact the Future of Biosimilars?

Multiple Inflation Reduction Act provisions impact biologics and biosimilars, but the net impact and potential consequences will vary across products.

States Turn to Drug Price Boards to Reduce Spending

State legislatures are increasingly considering prescription drug affordability boards and upper payment limits to lower state expenditures and patient costs.

How Do IRA Policies and the Enhancing Oncology Model Interact?

Manufacturers should adjust commercial and evidence generation strategies in response to the shifted incentives under the IRA and Enhancing Oncology Model.

Nicole Meyerson

CMS Best Price Discount Stacking Proposal May Trigger AMP Cap

Requiring manufacturers to stack all discounts provided through the supply chain could increase Medicaid rebate liability and complicate rebate dynamics.

340B Stakeholders Consider Impacts of Duplicate Discounts

Drug manufacturers, covered entities, and other 340B stakeholders have shown increased interest in 340B duplicate discounts.

Key Stakeholders of the 340B Drug Discount Program

Key 340B stakeholders include the federal government, patients, pharmacies, drug manufacturers, PBMs, plans, and the 340B prime vendor.

Ashley Flint

What Is the 340B Prescription Drug Discount Program?

Section 340B of the Public Health Service Act requires significant discounts on outpatient drugs for “covered entities"—safety-net providers and programs.

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